Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 12/20 | 0.48 |
| ▸ | MMP13 | P45452 | 10/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 4/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942802 | 0.94 | MMP1 (0.44) | MMP1ADAM17MMP13MMP2MMP9 | |
| SCHEMBL7951099 | 0.82 | ADAM17 (0.46) | MMP1ADAM17MMP13MMP2MMP9 | |
| SCHEMBL7354231 | 0.81 | ADAM17 (0.62) | MMP1ADAM17MMP13MMP2MMP9 | |
| SCHEMBL7362510 | 0.78 | ADAM17 (0.58) | MMP1ADAM17MMP13MMP2MMP9 | |
| SCHEMBL7353427 | 0.78 | ADAM17 (0.57) | MMP1ADAM17MMP13MMP2MMP9 | |
| SCHEMBL7421651 | 0.74 | MMP1 (0.46) | MMP1ADAM17MMP13ADAMTS4MMP2 | |
| SCHEMBL7358650 | 0.74 | ADAM17 (0.61) | MMP1ADAM17MMP13MMP2MMP9 | |
| SCHEMBL7952823 | 0.74 | ADAM17 (0.48) | MMP1ADAM17MMP13ADAMTS4MMP2 | |
| SCHEMBL7419988 | 0.74 | ADAM17 (0.49) | MMP1ADAM17MMP13ADAMTS4MMP2 | |
| SCHEMBL7430361 | 0.73 | ADAM17 (0.45) | MMP1ADAM17MMP13ADAMTS4MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268379-B1 | Substituted aryl hydroxamic acids as metalloproteinase inhibitors | DUPONT PHARMACEUTICALS COMPANY | 2001-07-31 | — | — | US | claimed |
| US-6268379-B1 | Substituted aryl hydroxamic acids as metalloproteinase inhibitors | DUPONT PHARMACEUTICALS COMPANY | 2001-07-31 | — | — | US | disclosed |