Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819593 | 0.87 | PARP10 (0.49) | TRPV1MAOBPARP10PARP15PARP14 | |
| SCHEMBL7567729 | 0.85 | MAOB (0.41) | TRPV1MAOBP2RX7CNR1HDAC6 | |
| SCHEMBL7639025 | 0.81 | MAOB (0.38) | TRPV1MAOB | |
| SCHEMBL7571112 | 0.81 | TRPV1 (0.37) | TRPV1MAOBKMT2ALMNAMAPT | |
| SCHEMBL7586530 | 0.79 | EPHX2 (0.38) | TRPV1MAOBP2RX7HDAC6 | |
| SCHEMBL7575627 | 0.78 | MPO (0.39) | PARP10P2RX7MTNR1AMTNR1B | |
| SCHEMBL7947443 | 0.78 | PARP10 (0.46) | PARP10P2RX7MTNR1AKMT2A | |
| SCHEMBL7947587 | 0.78 | MTNR1A (0.36) | TRPV1MAOBPARP10PARP15PARP14 | |
| SCHEMBL7567741 | 0.78 | HIF1A (0.51) | TRPV1NPC1P2RX7RAB9ACNR1 | |
| SCHEMBL7594084 | 0.77 | MAOB (0.51) | TRPV1MAOBCNR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |