Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575627 | 0.86 | MPO (0.39) | PARP10TAAR1CA12CA2CA9 | |
| SCHEMBL6819593 | 0.85 | PARP10 (0.49) | PARP10TAAR1KMT2AHIF1AOPRM1 | |
| SCHEMBL7567741 | 0.85 | HIF1A (0.51) | TAAR1HIF1AP2RX7 | |
| SCHEMBL7947587 | 0.85 | MTNR1A (0.36) | PARP10TAAR1MTNR1AHIF1AMAPK8 | |
| SCHEMBL7565696 | 0.82 | MTNR1A (0.54) | TAAR1CA12CA1CA2CA9 | |
| SCHEMBL6815624 | 0.82 | OPRM1 (0.51) | CA12CA2CA9KMT2AOPRM1 | |
| SCHEMBL6814668 | 0.80 | ST14 (0.42) | CA12CA1CA2CA9OPRM1 | |
| SCHEMBL7567769 | 0.79 | PARP15 (0.48) | PARP10TAAR1CA12CA1CA2 | |
| SCHEMBL6816015 | 0.78 | NPC1 (0.50) | KMT2AOPRM1OPRD1OPRK1PLA2G10 | |
| SCHEMBL7950464 | 0.78 | TRPV1 (0.39) | PARP10MTNR1AKMT2AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |