Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575627 | 0.86 | MPO (0.39) | MTNR1AP2RX7TAAR1HIF1AOPRM1 | |
| SCHEMBL7947443 | 0.85 | PARP10 (0.46) | MTNR1AP2RX7TAAR1HIF1AMAPK8 | |
| SCHEMBL6819593 | 0.85 | PARP10 (0.49) | TAAR1HIF1AOPRM1OPRD1OPRK1 | |
| SCHEMBL7567741 | 0.85 | HIF1A (0.51) | P2RX7TAAR1HIF1APOLBMAPT | |
| SCHEMBL7565696 | 0.82 | MTNR1A (0.54) | MTNR1ATAAR1MTNR1BPOLBMAPT | |
| SCHEMBL6815624 | 0.82 | OPRM1 (0.51) | OPRM1OPRD1OPRK1HSP90AA1PLA2G10 | |
| SCHEMBL7641136 | 0.79 | OPRM1 (0.38) | HIF1AMAPK8OPRM1OPRD1OPRK1 | |
| SCHEMBL6816015 | 0.78 | NPC1 (0.50) | OPRM1OPRD1OPRK1PLA2G10PLA2G2A | |
| SCHEMBL7567729 | 0.78 | MAOB (0.41) | P2RX7MAOBMAPTTRPV1 | |
| SCHEMBL7950464 | 0.78 | TRPV1 (0.39) | MTNR1AP2RX7PARP10MTNR1BMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |