Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | RARB | P10826 | 2/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030819 | 0.80 | HRH3 (0.43) | — | |
| SCHEMBL6650685 | 0.78 | NR1H2 (0.38) | — | |
| SCHEMBL6537049 | 0.77 | ALDH1A1 (0.30) | HSD17B10ALDH1A1HPGD | |
| SCHEMBL8462254 | 0.75 | HSD11B1 (0.41) | HSD11B1RARBPSMB5CA2CA1 | |
| SCHEMBL30684865 | 0.75 | HSD11B1 (0.56) | HSD11B1RARBPSMB5CA2CA1 | |
| SCHEMBL28829436 | 0.75 | HSD11B1 (0.56) | HSD11B1RARBPSMB5CA2CA1 | |
| SCHEMBL7034117 | 0.74 | HSD11B1 (0.38) | HSD11B1RARBPSMB5CA2CA1 | |
| SCHEMBL6650232 | 0.74 | PTGS2 (0.36) | HSD17B10ALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL28030817 | 0.73 | ALDH1A1 (0.35) | ALDH1A1HPGDTSHRSMN1; SMN2NPC1 | |
| SCHEMBL28031393 | 0.73 | PTGS2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001053356-A1 | CATALYST SYSTEM WITH A SELECTED TRANSITION METAL: COCATALYST RATIO | BASELL POLYOLEFINE GMBH (DE) | 2001-07-26 | — | — | WO | disclosed |