Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 3/20 | 0.45 |
| ▸ | BTK | Q06187 | 4/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PAK1 | Q13153 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956403 | 0.82 | GPR119 (0.54) | ALDH1A1HSD17B10NOS2NPC1RAB9A | |
| Bicarbonate SCHEMBL8746772 | 0.76 | KDM4E (0.43) | HSD17B10KDM4EHTTMEN1KMT2A | |
| SCHEMBL8914933 | 0.75 | BTK (0.47) | BTK | |
| SCHEMBL8746770 | 0.75 | BTK (0.47) | BTK | |
| SCHEMBL8490628 | 0.74 | PRCP (0.46) | BTKMEN1 | |
| SCHEMBL8490623 | 0.74 | PRCP (0.46) | BTKMEN1 | |
| SCHEMBL8918770 | 0.73 | POLB (0.50) | ALDH1A1SMN1; SMN2HPGDBTKMAPT | |
| SCHEMBL23323317 | 0.73 | CNR1 (0.51) | SMN1; SMN2MAPTMEN1KMT2APAK1 | |
| SCHEMBL8746781 | 0.73 | BTK (0.46) | KDM4EBTK | |
| SCHEMBL8746780 | 0.73 | BTK (0.46) | KDM4EBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300333-B1 | COMPOUNDS AS FUNGICIDES, MITICIDES OR INSECTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-10-09 | — | — | US | disclosed |