Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | BTK | Q06187 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18557416 | 0.85 | GPR119 (0.56) | GPR119CNR1CNR2ALDH1A1BTK | |
| SCHEMBL8746757 | 0.83 | BTK (0.44) | GPR119CNR1CNR2BTKIRAK4 | |
| SCHEMBL8746758 | 0.83 | BTK (0.44) | GPR119CNR1CNR2BTKIRAK4 | |
| SCHEMBL7950482 | 0.82 | ALDH1A1 (0.49) | CNR1CNR2ALDH1A1BTKNPC1 | |
| SCHEMBL11913046 | 0.81 | GPR119 (0.56) | GPR119CNR1CNR2ALDH1A1BTK | |
| SCHEMBL10137689 | 0.81 | GPR119 (0.56) | GPR119CNR1CNR2ALDH1A1BTK | |
| SCHEMBL7825491 | 0.80 | PIK3CD (0.52) | GPR119PIK3CD | |
| SCHEMBL11913075 | 0.80 | GPR119 (0.55) | GPR119CNR1CNR2ALDH1A1BTK | |
| SCHEMBL12596581 | 0.78 | GPR119 (0.52) | GPR119CNR1CNR2ALDH1A1BTK | |
| SCHEMBL12596651 | 0.78 | GPR119 (0.53) | GPR119CNR1CNR2ALDH1A1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300333-B1 | COMPOUNDS AS FUNGICIDES, MITICIDES OR INSECTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-10-09 | — | — | US | disclosed |