Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.47 |
| ▸ | BTK | Q06187 | 4/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914933 | 0.76 | BTK (0.47) | BTK | |
| SCHEMBL8746756 | 0.76 | BTK (0.41) | BTK | |
| SCHEMBL8746770 | 0.76 | BTK (0.47) | BTK | |
| SCHEMBL8746781 | 0.74 | BTK (0.46) | BTK | |
| SCHEMBL8746780 | 0.74 | BTK (0.46) | BTK | |
| SCHEMBL7950482 | 0.73 | ALDH1A1 (0.49) | MAPTHTTBTKMEN1ALDH1A1 | |
| SCHEMBL8488266 | 0.73 | KMT2A (0.41) | POLBMAPTBTKMEN1ALDH1A1 | |
| SCHEMBL8488267 | 0.73 | KMT2A (0.41) | POLBMAPTBTKMEN1ALDH1A1 | |
| SCHEMBL8483787 | 0.72 | BTK (0.37) | CHRM4BTK | |
| SCHEMBL8766684 | 0.72 | BTK (0.37) | CHRM4BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691321-A | INSECTICIDES, MITICIDES, PARASITICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1997-11-25 | — | — | US | disclosed |