Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818809 | 0.87 | CYP2D6 (0.34) | CYP2D6TSHRHPGD | |
| SCHEMBL819423 | 0.76 | MEN1 (0.41) | CYP2D6MC4RKMT2AALDH1A1P2RX7 | |
| SCHEMBL1009075 | 0.65 | CYP2D6 (0.32) | CYP2D6 | |
| SCHEMBL819176 | 0.65 | HSD11B1 (0.38) | HSD11B1ALDH1A1POLBHPGDKDM4E | |
| SCHEMBL8156905 | 0.64 | CYP2D6 (0.50) | CYP2D6MC4ROPRM1OPRD1OPRK1 | |
| SCHEMBL8156907 | 0.64 | CYP2D6 (0.50) | CYP2D6MC4ROPRM1OPRD1OPRK1 | |
| SCHEMBL6706135 | 0.63 | CYP2D6 (1.00) | CYP2D6MC4ROPRM1OPRD1OPRK1 | |
| SCHEMBL16226061 | 0.63 | CYP2D6 (1.00) | CYP2D6MC4ROPRM1OPRD1OPRK1 | |
| SCHEMBL7264542 | 0.63 | CYP2D6 (1.00) | CYP2D6MC4ROPRM1OPRD1OPRK1 | |
| SCHEMBL10035309 | 0.63 | CYP2D6 (0.54) | CYP2D6MC4ROPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087838-A1 | ALKYLIDENE COMPLEXES OF RUTHENIUM WITH N-HETEROCYCLIC CARBENE LIGANDS AND THEIR USE AS HIGHLY ACTIVE, SELECTIVE CATALYSTS FOR OLEFIN METATHESIS | Aventis Research & Technologies GmbH & Co. KG (DE) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999051344-A1 | ALKYLIDENE COMPLEXES OF RUTHENIUM WITH N-HETEROCYCLIC CARBENE LIGANDS AND THEIR USE AS HIGHLY ACTIVE, SELECTIVE CATALYSTS FOR OLEFIN METATHESIS | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-10-14 | — | — | WO | disclosed |