Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4816582 | 0.90 | MBOAT4 (0.37) | MAPK1LMNACYP1A2ENPP1CRHR1 | |
| SCHEMBL7960560 | 0.89 | LMNA (0.47) | MAPK1LMNACYP1A2ENPP1CRHR1 | |
| SCHEMBL4819883 | 0.87 | KDM4E (0.41) | MAPK1LMNACYP1A2ENPP1CRHR1 | |
| SCHEMBL7492832 | 0.87 | LMNA (0.38) | MAPK1LMNACYP1A2ENPP1CRHR1 | |
| SCHEMBL4819244 | 0.86 | MAPK1 (0.38) | MAPK1LMNACYP1A2ENPP1CRHR1 | |
| SCHEMBL4817223 | 0.85 | ALDH1A1 (0.35) | MAPK1LMNACYP1A2ENPP1CRHR1 | |
| SCHEMBL4820870 | 0.84 | ENPP1 (0.38) | MAPK1LMNACYP1A2ENPP1ALDH1A1 | |
| SCHEMBL6188333 | 0.83 | LMNA (0.35) | MAPK1LMNACYP1A2CRHR1THRB | |
| SCHEMBL4819349 | 0.83 | CRHR1 (0.38) | MAPK1LMNACYP1A2ENPP1CRHR1 | |
| SCHEMBL4821705 | 0.81 | LMNA (0.34) | MAPK1LMNACYP1A2CRHR1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242451-B1 | Fungicidal trihalophenyl-triazolopyrimidines | BASF AKTIENGESELLSCHAFT | 2001-06-05 | — | — | US | claimed |
| US-5985883-A | FUNGICIDAL ACTIVITY AGAINST RICE BLAST DISEASE | AMERICAN CYANAMID COMPANY (US) | 1999-11-16 | — | — | US | claimed |
| US-6242451-B1 | Fungicidal trihalophenyl-triazolopyrimidines | BASF AKTIENGESELLSCHAFT | 2001-06-05 | — | — | US | disclosed |
| US-5985883-A | FUNGICIDAL ACTIVITY AGAINST RICE BLAST DISEASE | AMERICAN CYANAMID COMPANY (US) | 1999-11-16 | — | — | US | disclosed |