Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455125 | 0.80 | SLC6A4 (0.37) | MAOAMAOBADRA2AADRA2BADRA2C | |
| SCHEMBL1454315 | 0.79 | SLC6A4 (0.36) | MAOAMAOBADRA2AADRA2BADRA2C | |
| SCHEMBL1455296 | 0.76 | MTNR1A (0.45) | MAOAMAOBADRA2AADRA2BADRA2C | |
| SCHEMBL1455116 | 0.71 | SLC6A4 (0.35) | MAOAMAOBADRA2AADRA2BADRA2C | |
| SCHEMBL1454212 | 0.70 | MTNR1A (0.42) | MAOAMAOBADRA2AADRA2BADRA2C | |
| SCHEMBL1454451 | 0.70 | SLC7A5 (0.36) | MAOAMAOBADRA2AADRA2BADRA2C | |
| SCHEMBL9770515 | 0.68 | SLC6A4 (0.38) | MAOAMAOBADRA2AADRA2BADRA2C | |
| SCHEMBL1454232 | 0.67 | SLC6A4 (0.37) | POLBKDM4ESLC6A4MTNR1AMTNR1B | |
| SCHEMBL1454220 | 0.66 | POLB (0.36) | MAOAMAOBADRA2AADRA2BADRA2C | |
| SCHEMBL27658477 | 0.66 | AOX1 (0.41) | MAOAMAOBADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262197-B1 | AS POLYMERIZATION CATALYST IN OLEFIN POLYMERIZATION | TARGOR GMBH (DE) | 2001-07-17 | — | — | US | disclosed |
| EP-0739897-A1 | Polynuclear metallocene compound, process for preparing it and its use as catalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-30 | — | — | EP | disclosed |