SCHEMBL1454232

SCHEMBL1454232

C[CH]CC(CCC)Oc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 2/20 0.37
PPARG P37231 3/20 0.36
PPARA Q07869 3/20 0.36
LTA4H P09960 3/20 0.34
POLB P06746 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
KDM4C Q9H3R0 1/20 0.32
CTSK P43235 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1454165 0.90 LTA4H (0.40) SLC6A4PPARGPPARALTA4HCTSK
SCHEMBL1454220 0.85 POLB (0.36) SLC6A4PPARGPPARALTA4HPOLB
SCHEMBL7841888 0.85 SLC6A4 (0.43) SLC6A4PPARGPPARALTA4HPOLB
SCHEMBL1454315 0.84 SLC6A4 (0.36) SLC6A4PPARGPPARALTA4HPOLB
SCHEMBL11065085 0.81 PPARG (0.44) SLC6A4PPARGPPARALTA4HKDM4E
SCHEMBL23974956 0.78 PPARG (0.41) SLC6A4PPARGPPARALTA4HPOLB
SCHEMBL8349925 0.78 SLC6A4 (0.39) SLC6A4PPARGPPARALTA4HPOLB
SCHEMBL14844285 0.78 LTA4H (0.44) SLC6A4PPARGPPARALTA4HCTSK
SCHEMBL9770515 0.76 SLC6A4 (0.38) SLC6A4PPARGPPARALTA4HPOLB
SCHEMBL5050475 0.76 LTA4H (0.44) SLC6A4PPARGPPARALTA4HALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7910617-B2 Method for suppressing the number of peripheral blood lymphocytes using an amino alcohol compound SANKYO COMPANY, LIMITED (JP) 2011-03-22 US disclosed
US-20070191468-A1 Amino alcohol compound DAIICHI SANKYO COMPANY, LIMITED (JP) 2007-08-16 US disclosed
EP-1733724-A1 AMINO ALCOHOL COMPOUND Sankyo Company, Limited (JP) 2006-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070191468-A1 Amino alcohol compound ADH1A, ADH1C, BCAT1 SLC6A4 1912/4885PPARG 388/4885PPARA 295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.