SCHEMBL7951841

SCHEMBL7951841

CCOC(=O)C(CNC(=O)[C@@H]1CCCN(C(=O)C(CCC2CCN(C(=O)O)CC2)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1)NS(=O)(=O)c1ccc2ccccc2c1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
F10 P00742 6/20 0.47
F2 P00734 10/20 0.47
PLAU P00749 2/20 0.45
PLG P00747 1/20 0.43
HPN P05981 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6976329 0.86 F2 (0.44) F10F2PLAUPLG
SCHEMBL6969381 0.86 ITGB3 (0.43) F10F2PLAUPLG
SCHEMBL6973599 0.85 ITGB3 (0.44) F10F2PLAUPLG
SCHEMBL6971548 0.85 F2 (0.43) F10F2PLAUPLG
SCHEMBL6973594 0.85 ITGB3 (0.44) F10F2PLAUPLG
SCHEMBL6971755 0.84 F2 (0.46) F10F2PLAUPLG
SCHEMBL6976118 0.83 F2 (0.44) F10F2PLAUPLG
SCHEMBL7754664 0.83 ALDH1A1 (0.48)
SCHEMBL7494534 0.82 ITGB3 (0.51)
SCHEMBL6975339 0.80 MMP13 (0.44) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6333338-B1 ANTICOAGULANTS, CARDIOVASCULAR DISORDERS LABORATOIRE L. LAFON (FR) 2001-12-25 US disclosed