Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 15/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976930 | 0.92 | TGFBR1 (0.45) | TGFBR1MMP13 | |
| SCHEMBL7951214 | 0.90 | TGFBR1 (0.44) | TGFBR1MMP13 | |
| SCHEMBL6969887 | 0.90 | TGFBR1 (0.49) | TGFBR1MMP13 | |
| SCHEMBL7943420 | 0.89 | TGFBR1 (0.47) | TGFBR1 | |
| SCHEMBL6976329 | 0.89 | F2 (0.44) | ALDH1A1TGFBR1MMP13 | |
| SCHEMBL6962633 | 0.88 | MMP13 (0.49) | TGFBR1MMP13 | |
| SCHEMBL6964258 | 0.88 | MMP13 (0.50) | TGFBR1MMP13 | |
| SCHEMBL6964185 | 0.88 | GPR119 (0.48) | MMP13 | |
| SCHEMBL6968993 | 0.87 | MMP13 (0.50) | TGFBR1MMP13 | |
| SCHEMBL6963385 | 0.87 | STS (0.46) | ALDH1A1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |