SCHEMBL4159987

SCHEMBL4159987

O=C(O)CNC(CO)CO

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.35
SRR Q9GZT4 1/20 0.35
LMNA P02545 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
CNR1 P21554 1/20 0.35
ADRA1A P35348 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
PTGS2 P35354 1/20 0.34
OR51E2 Q9H255 2/20 0.33
GLRA1 P23415 1/20 0.33
SLC6A9 P48067 1/20 0.33
ABCC3 O15438 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CTH P32929 1/20 0.32
EGLN1 Q9GZT9 1/20 0.31
ECE1 P42892 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1643592 0.85 LMNA (0.56) LMNATDP1CNR1ADRA1AKDM4E
SCHEMBL26142063 0.82 MME (0.39) LMNATDP1CNR1ADRA1AKDM4E
SCHEMBL6695804 0.82 GLRA1 (0.36) LMNAOR51E2GLRA1SLC6A9
SCHEMBL20599906 0.79 PTPN1 (0.35) LDHASRRLMNATDP1ALDH1A1
SCHEMBL3132707 0.76 MAPK1 (0.55) KDM4EALDH1A1MAPTECE1
SCHEMBL1742036 0.76
SCHEMBL26292894 0.76 TDP1 (0.39) LMNATDP1CNR1ADRA1AKDM4E
SCHEMBL7044031 0.76 MME (0.41) LMNATDP1CNR1ADRA1AKDM4E
SCHEMBL16267385 0.74 MME (0.39) LMNATDP1CNR1ADRA1AKDM4E
SCHEMBL3049168 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0569132-A1 Improvements in radiolabelling JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1993-11-10 EP claimed
JP-6065169-A None JP disclosed
US-20250287937-A1 COMPOSITIONS AND METHODS FOR REDUCING ICE CRYSTAL FORMATION X-THERMA, INC. (US) 2025-09-18 US disclosed
US-12391799-B2 Peptoid polymers and methods of use X-THERMA, INC. (US) 2025-08-19 US disclosed
US-12137682-B2 Compositions and methods for reducing ice crystal formation X-THERMA, INC. (US) 2024-11-12 US disclosed
CN-110769689-B Novel supercooling method for preserving biological samples 先时迈纳米生物科技股份有限公司 2024-04-26 CN disclosed
EP-3609906-B1 NOVEL PEPTOID POLYMERS AND METHODS OF USE X THERMA INC (US) 2024-03-20 EP disclosed
US-20240084074-A1 NOVEL PEPTOID POLYMERS AND METHODS OF USE X-THERMA, INC. (US) 2024-03-14 US disclosed
US-20230292741-A1 NOVEL SUPERCOOLING METHODS FOR PRESERVATION OF BIOLOGICAL SAMPLES X-THERMA, INC. (US) 2023-09-21 US disclosed
US-20230292741-A1 NOVEL SUPERCOOLING METHODS FOR PRESERVATION OF BIOLOGICAL SAMPLES X-THERMA, INC. (US) 2023-09-21 US disclosed
WO-2007054288-A1 REPAIR FILM AND USE THEREOF BASF COATINGS AG (DE) 2007-05-18 WO disclosed
WO-2007054289-A2 AQUEOUS POWDER DISPERSION, WHICH CAN BE CURED BY RADICAL POLYMERIZATION, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE BASF COATINGS AG (DE) 2007-05-18 WO disclosed
WO-2005009963-A1 CHELANTS AND MACROCYCLIC METAL COMPLEX RADIOPHARMACEUTICALS TIHEREOF BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2005-02-03 WO disclosed
US-20050008575-A1 Chelants and macrocyclic metal complex radiopharmaceuticals thereof LANTHEUS MEDICAL IMAGING, INC. 2005-01-13 US disclosed
US-20050010038-A1 Chelants and macrocyclic metal complex radiopharmaceuticals thereof BRISTOL-MYERS SQUIBB PHARMA COMPANY 2005-01-13 US disclosed
US-6346547-B1 TREATING ATHEROSCLEROSIS, RESTENOSIS AND STROKE CHECKPOINT, GENETICS, INC. 2002-02-12 US disclosed
EP-0569132-B1 Improvements in radiolabelling ANORMED INC (CA) 2000-03-01 EP disclosed
US-5350837-A Complexes with 99m Tc suitable for radiolabelling monoclonal antibodies or other macro molecules JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1994-09-27 US disclosed
JP-H0665169-A IMPROVED RADIOLABELLING JOHNSON MATTHEY PLC 1994-03-08 JP disclosed
EP-0569132-A1 Improvements in radiolabelling JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1993-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250287937-A1 COMPOSITIONS AND METHODS FOR REDUCING ICE CRYSTAL FORMATION CUTA, IAPP, CRYAA LDHA 3237/4885SRR 2586/4885LMNA 670/4885
US-12391799-B2 Peptoid polymers and methods of use IAPP, CUTA, VIP LDHA 3263/4885SRR 2870/4885LMNA 951/4885
US-20240084074-A1 NOVEL PEPTOID POLYMERS AND METHODS OF USE CUTA, IAPP, CRYAA LDHA 3573/4885SRR 2712/4885LMNA 1046/4885
US-12137682-B2 Compositions and methods for reducing ice crystal formation CUTA, IAPP, CRYAA LDHA 3237/4885SRR 2586/4885LMNA 670/4885
US-20050008575-A1 Chelants and macrocyclic metal complex radiopharmaceuticals thereof TFRC, HLCS, CLTC LDHA 3253/4885SRR 1175/4885LMNA 3591/4885
US-20050010038-A1 Chelants and macrocyclic metal complex radiopharmaceuticals thereof TFRC, HLCS, CLTC LDHA 3253/4885SRR 1175/4885LMNA 3591/4885
US-20230292741-A1 NOVEL SUPERCOOLING METHODS FOR PRESERVATION OF BIOLOGICAL SAMPLES PPIG, AQP3, AQP1 LDHA 2665/4885SRR 2955/4885LMNA 195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.