Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 11/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952055 | 0.79 | ALDH1A1 (0.42) | CYP3A4TBXAS1 | |
| SCHEMBL7950943 | 0.76 | CRBN (0.33) | ADH5CYP3A4TBXAS1 | |
| Water SCHEMBL6553144 | 0.75 | CYP3A4 (0.36) | ADH5CA12CA9CYP3A4TBXAS1 | |
| SCHEMBL27404500 | 0.72 | CA12 (0.52) | CA12CA2CA4CA7CA9 | |
| SCHEMBL6617400 | 0.69 | NCOA3 (0.36) | CA12CA2CA9CYP3A4 | |
| SCHEMBL7957441 | 0.67 | CA12 (0.46) | CA12CA2CA4CA7CA9 | |
| SCHEMBL6617261 | 0.66 | CRBN (0.38) | ADH5CA12CA9CYP3A4 | |
| SCHEMBL28267134 | 0.66 | ADH5 (0.55) | ADH5CYP4Z1CYP3A4BAZ2BTBXAS1 | |
| SCHEMBL62049 | 0.65 | ADH5 (0.90) | ADH5CYP4Z1CYP3A4BAZ2BTBXAS1 | |
| SCHEMBL7957187 | 0.65 | HCAR3 (0.45) | CA12CA2CA4CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1081633-C | 1,2, 4-benzothiadiazine derivatives, method for preparing same and use thereof | NOVO NORDISK AS (DK) | 2002-03-27 | — | — | CN | disclosed |
| US-6242443-B1 | 1,2,4-benzothiadiazine derivatives, their preparation and use | NOVO NORDISK AIS (DK) | 2001-06-05 | — | — | US | disclosed |
| CN-1222910-A | 1,2, 4-benzothiadiazine derivatives, method for preparing same and use thereof | NOVO NORDISK AS (DK) | 1999-07-14 | — | — | CN | disclosed |