Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.70 |
| ▸ | MAPT | P10636 | 6/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 4/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265992 | 0.88 | SIRT2 (0.73) | SIRT2L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL7148635 | 0.86 | SIRT2 (0.70) | SIRT2L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL29376403 | 0.84 | HTR1A (0.71) | SIRT2L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL7296066 | 0.84 | SIRT2 (0.75) | SIRT2L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL1220782 | 0.83 | SMN1; SMN2 (0.66) | SIRT2L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL14788168 | 0.83 | SIRT2 (0.74) | SIRT2L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL8900040 | 0.83 | LMNA (0.66) | SIRT2L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL17513948 | 0.83 | SIRT2 (0.65) | SIRT2L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL101993 | 0.82 | SIRT2 (0.65) | SIRT2L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL16975850 | 0.82 | SMN1; SMN2 (0.71) | L3MBTL1MAPTNPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262030-B1 | Erythromycin derivatives | PFIZER INC. | 2001-07-17 | — | — | US | claimed |