SCHEMBL7952409

SCHEMBL7952409

N#CCSc1ccc(F)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.52
MAOB P27338 2/20 0.52
ALDH1A1 P00352 3/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
KDM4E B2RXH2 1/20 0.41
GLA P06280 1/20 0.41
HPGD P15428 1/20 0.41
GAA P10253 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
CTSK P43235 1/20 0.38
PDE10A Q9Y233 2/20 0.35
CYP1A2 P05177 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CRBN Q96SW2 1/20 0.34
NPC1 O15118 1/20 0.34
POLB P06746 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13791015 0.77 MAOB (0.55) MAOAMAOBALDH1A1
SCHEMBL7879574 0.77 MAOA (0.52) MAOAMAOBALDH1A1KMT2AMAPT
SCHEMBL3238761 0.77 MAOA (0.43) MAOAMAOBALDH1A1KMT2AMAPT
SCHEMBL5178452 0.77 NR1H2 (0.44) ALDH1A1KMT2AMAPTMEN1LMNA
SCHEMBL10395941 0.77 HPGD (0.47) ALDH1A1KMT2AMAPTMEN1LMNA
SCHEMBL7964774 0.77 KIF11 (0.42) ALDH1A1KMT2AMEN1KDM4ECTSK
SCHEMBL1931888 0.76 ALDH1A1 (0.52) MAOAMAOBALDH1A1KMT2AMAPT
SCHEMBL6571993 0.76 MAOB (0.38) MAOAMAOBKMT2AMAPTLMNA
SCHEMBL11620098 0.75 MAOA (0.46) MAOAMAOB
Hydrogen Sulfide SCHEMBL7174224 0.74 ALDH1A1 (0.50) MAOAMAOBALDH1A1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9466827-B2 Secondary battery NEC CORPORATION (JP) 2016-10-11 US disclosed
US-20130164605-A1 SECONDARY BATTERY NEC CORPORATION (JP) 2013-06-27 US disclosed
US-6225346-B1 FOR THERAPY AND PROPHYLAXIS OF CELL PROLIFERATIVE DISORDERS OR CELL DIFFERENTIATION DISORDERS ASSOCIATED WITH PARTICULAR TYROSINE KINASES BY INHIBITING ONE OR MORE ABNORMAL TYROSINE KINASE ACTIVITIES SUGEN, INC. 2001-05-01 US disclosed
US-5935993-A TYROSINE KINASE INHIBITORS; TREATMENT OF CELL GROWTH, CELL DIFFERENTIATION DISORDERS SUGEN, INC. (US) 1999-08-10 US disclosed
US-5891917-A MODULATING TYROSINE SIGNAL TRANSDUCTION TO PREVENT AND TREAT CELL PROLIFERATIVE DISORDERS OR CELL DIFFERENTIATION DISORDERS ASSOCIATED WITH PARTICULAR TYROSINE KINASES BY INHIBITING ONE OR MORE ABNORMAL TYROSINE KINASE ACTIVITIES SUGEN, INC. (US) 1999-04-06 US disclosed
WO-1996040629-A1 TYRPHOSTIN-LIKE COMPOUNDS FOR THE TREATMENT OF CELL PROLIFERATIVE DISORDERS OR CELL DIFFERENTIATION DISORDERS SUGEN, INC. (US) 1996-12-19 WO disclosed