SCHEMBL7879574

SCHEMBL7879574

N#CCSc1ccc(Cl)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.52
MAOB P27338 4/20 0.52
ALDH1A1 P00352 5/20 0.42
NPC1 O15118 3/20 0.42
KMT2A Q03164 3/20 0.42
RAB9A P51151 3/20 0.42
MEN1 O00255 2/20 0.42
MAPT P10636 2/20 0.39
IDO1 P14902 1/20 0.39
SOD1 P00441 1/20 0.39
NPSR1 Q6W5P4 3/20 0.39
KDM4E B2RXH2 1/20 0.39
CTSK P43235 1/20 0.38
TEAD1 P28347 1/20 0.38
YAP1 P46937 1/20 0.38
TEAD4 Q15561 1/20 0.38
TEAD2 Q15562 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
LMNA P02545 2/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11617330 0.78 MAOA (0.49) MAOAMAOBALDH1A1NPC1KMT2A
SCHEMBL2320892 0.77 MAOA (0.43) MAOAMAOBALDH1A1NPC1KMT2A
SCHEMBL6815652 0.77 SOD1 (0.40) MAOAMAOBALDH1A1KMT2AMEN1
SCHEMBL10959400 0.77 CA12 (0.53) MAOAMAOBALDH1A1NPC1KMT2A
SCHEMBL10395941 0.77 HPGD (0.47) ALDH1A1NPC1KMT2ARAB9AMEN1
SCHEMBL5178452 0.77 NR1H2 (0.44) ALDH1A1NPC1KMT2ARAB9AMEN1
SCHEMBL13791015 0.77 MAOB (0.55) MAOAMAOBALDH1A1IDO1CYP2A6
SCHEMBL7952409 0.77 MAOA (0.52) MAOAMAOBALDH1A1NPC1KMT2A
SCHEMBL6812238 0.77 DAO (0.39) MAOAMAOBALDH1A1MAPTIDO1
SCHEMBL1931888 0.76 ALDH1A1 (0.52) MAOAMAOBALDH1A1NPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5710100-A ANTIDOTES WITH HERBICIDES FOR CROPS SUCH AS CORN MONSANTO COMPANY (US) 1998-01-20 US claimed
US-20240018081-A1 METHOD FOR PRODUCING ORGANIC FLUORINE COMPOUNDS DAIKIN INDUSTRIES, LTD. (JP) 2024-01-18 US disclosed
WO-2017060488-A1 NEW TRPA1 ANTAGONISTS ALMIRALL, S.A. (ES) 2017-04-13 WO disclosed
EP-1304316-B1 PROCESSES FOR THE PRODUCTION OF FLUORINATED ORGANIC COMPOUNDS AND FLUORINATING AGENTS DAIKIN IND LTD (JP) 2011-08-10 EP disclosed
US-7311890-B2 Process for the production of fluorinated organic compounds and fluorinating agents DAIKIN INDUSTRIES, LTD. (JP) 2007-12-25 US disclosed
US-7311890-B2 Process for the production of fluorinated organic compounds and fluorinating agents DAIKIN INDUSTRIES, LTD. (JP) 2007-12-25 US disclosed
US-6326500-B1 ANTIINFLAMMATORY AGENTS; ANTIALLERGENS ABBOTT LABORATORIES 2001-12-04 US disclosed
US-6215001-B1 ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION KNOLL AKTIENGESELLSCHAFT (DE) 2001-04-10 US disclosed
US-6031109-A Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents KNOLL AKTIENGESELLSCHAFT (DE) 2000-02-29 US disclosed
US-5780642-A NON-STEROIDAL ANTIINFLAMMATORY AGENT WHICH BLOCKS RELEASE OF ARACHIDONIC ACID FROM PHOSPHOLIPIDS; SIDE EFFECT REDUCTION KNOLL AKTIENGESELLSCHAFT (DE) 1998-07-14 US disclosed
EP-0705251-A1 IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS Knoll AG (DE) 1996-04-10 EP disclosed
WO-1995000493-A1 IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS KNOLL AG (DE) 1995-01-05 WO disclosed
US-4675316-A FUNGICIDES ROHM AND HAAS COMPANY (US) 1987-06-23 US disclosed
EP-0031938-B1 USE OF ARYLOXY(THIO)CARBOXYLIC ACID NITRILES AND AMIDOXIMES AS ANTIDOTES AGAINST HERBICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1985-03-27 EP disclosed
US-4414020-A AMIDOXIMES AS SAFENING AGENTS HOECHST AG (DE) 1983-11-08 US disclosed
US-3994976-A Substituted phenylthioamidines THE DOW CHEMICAL COMPANY (US) 1976-11-30 US disclosed
US-3933912-A Substituted phenylthioamidines THE DOW CHEMICAL COMPANY (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018081-A1 METHOD FOR PRODUCING ORGANIC FLUORINE COMPOUNDS PFAS, FBL, FLNB MAOA 189/4885MAOB 75/4885ALDH1A1 1098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.