Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | F2RL1 | P55085 | 9/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7016531 | 0.73 | ALDH1A1 (0.42) | ADRA2AADRA2BADRA2CFPR2KMT2A | |
| SCHEMBL11211322 | 0.69 | TAAR1 (0.47) | TAAR1MTORADKNISCHKMT2A | |
| SCHEMBL6037395 | 0.69 | KMT2A (0.47) | TAAR1KMT2A | |
| Bromide SCHEMBL28351579 | 0.69 | FPR2 (0.43) | ADRA2AADRA2BADRA2CF2RL1FPR2 | |
| SCHEMBL7950652 | 0.68 | ADRA2A (0.37) | TAAR1ADRA2AADRA2BADRA2CF2RL1 | |
| SCHEMBL6432858 | 0.68 | KMT2A (0.46) | TAAR1KMT2A | |
| SCHEMBL954734 | 0.67 | CHRM2 (0.45) | TAAR1ADRA2AADRA2BADRA2CF2RL1 | |
| SCHEMBL4442877 | 0.67 | TAAR1 (0.49) | TAAR1ADRA2AADRA2BADRA2CF2RL1 | |
| SCHEMBL12011595 | 0.67 | NISCH (0.49) | TAAR1ADRA2AADRA2BADRA2CMTOR | |
| SCHEMBL9052552 | 0.67 | TAAR1 (0.41) | TAAR1ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255305-B1 | PSYCHOLOGICAL DISORDERS | MERCK SHARP & DOHME LIMITED (GB) | 2001-07-03 | — | — | US | disclosed |