Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11333762 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL26611803 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL31436766 | 0.79 | APP (0.57) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL6191956 | 0.78 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL16914813 | 0.78 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL28337285 | 0.75 | RAB9A (0.54) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL28847978 | 0.75 | HPGD (0.43) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL29651055 | 0.75 | LMNA (0.68) | KDM4EALDH1A1HPGDMAPTGAA | |
| SCHEMBL462088 | 0.75 | LMNA (0.68) | KDM4EALDH1A1HPGDMAPTGAA | |
| SCHEMBL14072437 | 0.75 | ADORA3 (0.68) | KDM4EALDH1A1HPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258815-B1 | HETEROCYCLIC COMPOUNDS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 2001-07-10 | — | — | US | claimed |
| US-6258815-B1 | HETEROCYCLIC COMPOUNDS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 2001-07-10 | — | — | US | disclosed |
| US-4288362-A | Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-08 | — | — | US | disclosed |