Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29033598 | 0.85 | ADORA3 (0.62) | ADORA3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL17753301 | 0.84 | ADORA3 (0.61) | ADORA3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL17753303 | 0.84 | ADORA3 (0.61) | ADORA3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13995844 | 0.84 | ADORA3 (0.61) | ADORA3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8198639 | 0.84 | ADORA3 (0.61) | ADORA3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11487364 | 0.81 | ADORA3 (0.58) | ADORA3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31060760 | 0.81 | ADORA3 (1.00) | ADORA3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7417909 | 0.80 | ADORA3 (0.57) | ADORA3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30725575 | 0.80 | ADORA3 (0.57) | ADORA3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7423796 | 0.78 | ADORA3 (0.55) | ADORA3KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105601621-B | Nitrogen-containing polycyclic compound and organic electroluminescent device using the same | 株式会社LG化学 | 2019-05-28 | — | — | CN | disclosed |
| US-9698358-B2 | Nitrogen-containing polycyclic compound and organic electroluminescent device using the same | LG CHEM, LTD. (KR) | 2017-07-04 | — | — | US | disclosed |
| US-9698358-B2 | Nitrogen-containing polycyclic compound and organic electroluminescent device using the same | LG CHEM, LTD. (KR) | 2017-07-04 | — | — | US | disclosed |
| US-9698358-B2 | Nitrogen-containing polycyclic compound and organic electroluminescent device using the same | LG CHEM, LTD. (KR) | 2017-07-04 | — | — | US | disclosed |
| CN-105601621-A | Nitrogen-containing polycyclic compound and organic electroluminescent device using the same | LG CHEMICAL LTD | 2016-05-25 | — | — | CN | disclosed |
| US-20160141518-A1 | NITROGEN-CONTAINING POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2016-05-19 | — | — | US | disclosed |
| US-20160141518-A1 | NITROGEN-CONTAINING POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2016-05-19 | — | — | US | disclosed |
| US-20160141518-A1 | NITROGEN-CONTAINING POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2016-05-19 | — | — | US | disclosed |
| WO-2008109179-A1 | METALLOPROTEASE INHIBITORS CONTAINING A SQUARAMIDE MOIETY | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-09-12 | — | — | WO | disclosed |
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-09-11 | — | — | US | disclosed |
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-09-11 | — | — | US | disclosed |
| US-20080221094-A1 | Metalloprotease inhibitors containing a squaramide moiety | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-09-11 | — | — | US | disclosed |
| US-20080221094-A1 | Metalloprotease inhibitors containing a squaramide moiety | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | MMP12, MMP13, MMP25 | ADORA3 3364/4885KDM4E 693/4885ALDH1A1 714/4885 |
| US-20080221094-A1 | Metalloprotease inhibitors containing a squaramide moiety | MMP13, MMP14, MMP11 | ADORA3 2726/4885KDM4E 686/4885ALDH1A1 1641/4885 |
| US-20160141518-A1 | NITROGEN-CONTAINING POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | NCL, ODC1, PNMT | ADORA3 3413/4885KDM4E 1318/4885ALDH1A1 3323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.