Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GPR3 | P46089 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 8/20 | 0.40 |
| ▸ | GABRP | O00591 | 3/20 | 0.40 |
| ▸ | GABRD | O14764 | 3/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.40 |
| ▸ | GABRE | P78334 | 3/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23212272 | 0.77 | ALDH1A1 (0.48) | ALDH1A1GPR3HSD17B10AHRKIF11 | |
| SCHEMBL1426545 | 0.77 | KIF11 (0.48) | ALDH1A1GPR3HSD17B10AHRKIF11 | |
| SCHEMBL11597870 | 0.77 | ALDH1A1 (0.48) | ALDH1A1GPR3HSD17B10AHRKIF11 | |
| SCHEMBL8482653 | 0.77 | ALDH1A1 (0.48) | ALDH1A1GPR3HSD17B10AHRKIF11 | |
| SCHEMBL10890967 | 0.77 | ALDH1A1 (0.48) | ALDH1A1GPR3HSD17B10AHRKIF11 | |
| SCHEMBL1323291 | 0.74 | ESR1 (0.47) | ALDH1A1GPR3HSD17B10AHRKIF11 | |
| SCHEMBL328893 | 0.73 | ALDH1A1 (0.43) | ALDH1A1GPR3HSD17B10AHRKIF11 | |
| SCHEMBL5216846 | 0.73 | KIF11 (0.49) | ALDH1A1GPR3HSD17B10AHRKIF11 | |
| SCHEMBL6897737 | 0.73 | ALDH1A1 (0.45) | ALDH1A1GPR3HSD17B10AHRKIF11 | |
| SCHEMBL9010052 | 0.73 | KIF11 (0.49) | ALDH1A1GPR3HSD17B10AHRKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123739-B1 | ALPHA-SUBSTITUTED-ALKYLARYLKETALS PARTICULARLY USEFUL FOR PREPARING ALPHA-ARYLALKANOIC ACIDS | ZAMBON S.p.A. (IT) | 1987-11-19 | — | — | EP | claimed |
| US-4535166-A | Process for preparing alpha-arylalkanoic acids | ZAMBON S.P.A. (IT) | 1985-08-13 | — | — | US | claimed |
| US-6268526-B1 | MIXTURE FORMED FROM AN AROMATIC SUBSTITUTED ALCOHOL AND/OR AN AROMATIC SUBSTITUTED ALKYL HALIDE, AND A COPPER-FREE PALLADIUM CATALYST IS CARBONYLATED WITH CARBON MONOXIDE TO PRODUCE ALPHA-SUBSTITUTED CARBOXYLIC ACID OR ESTER | ALBEMARLE CORPORATION | 2001-07-31 | — | — | US | disclosed |
| WO-2000035849-A1 | PALLADIUM CATALYZED CARBONYLATION PROCESS | ALBEMARLE CORPORATION (US) | 2000-06-22 | — | — | WO | disclosed |
| EP-0152004-B1 | PROCESS FOR PREPARING ALPHA-ARYL-ALKANOIC ACIDS | ZAMBON S.p.A. (IT) | 1988-05-25 | — | — | EP | disclosed |
| EP-0153701-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE ALPHA-ARYLALKANOIC ACIDS | ZAMBON S.p.A. (IT) | 1988-04-27 | — | — | EP | disclosed |
| EP-0123739-B1 | ALPHA-SUBSTITUTED-ALKYLARYLKETALS PARTICULARLY USEFUL FOR PREPARING ALPHA-ARYLALKANOIC ACIDS | ZAMBON S.p.A. (IT) | 1987-11-19 | — | — | EP | disclosed |
| EP-0151817-B1 | PROCESS FOR PREPARING ALPHA-ARYLALKANOIC ACIDS | ZAMBON S.p.A. (IT) | 1986-12-03 | — | — | EP | disclosed |
| US-4620031-A | Process for preparing alpha-aryl-alkanoic acids | ZAMBON S.P.A. (IT) | 1986-10-28 | — | — | US | disclosed |
| US-4618697-A | Process for preparing alpha-arylalkanoic acids | ZAMBON SPA (IT) | 1986-10-21 | — | — | US | disclosed |
| US-4582930-A | Process for the preparation of optically active alpha-arylalkanoic acids | ZAMBON S.P.A. (IT) | 1986-04-15 | — | — | US | disclosed |
| US-4579968-A | Process for the preparation of optically active alpha-arylalkanoic acids | ZAMBON S.P.A. (IT) | 1986-04-01 | — | — | US | disclosed |
| EP-0101124-B1 | PROCESS FOR PREPARING ALPHA ARYLALKANOIC ACIDS | ZAMBON S.p.A. (IT) | 1986-01-29 | — | — | EP | disclosed |
| EP-0154853-A1 | Process for the preparation of optically active alpha-arylalkanoic acids | ZAMBON S.p.A. (IT) | 1985-09-18 | — | — | EP | disclosed |
| US-4537979-A | Alpha-substituted-alkylarylketals particularly useful for preparing alpha-arylalkanoic acids | ZAMBON S.P.A. (IT) | 1985-08-27 | — | — | US | disclosed |
| EP-0151817-A1 | Process for preparing alpha-arylalkanoic acids | ZAMBON S.p.A. (IT) | 1985-08-21 | — | — | EP | disclosed |
| US-4535166-A | Process for preparing alpha-arylalkanoic acids | ZAMBON S.P.A. (IT) | 1985-08-13 | — | — | US | disclosed |
| EP-0101124-A1 | Process for preparing alpha arylalkanoic acids | ZAMBON S.p.A. (IT) | 1984-02-22 | — | — | EP | disclosed |