SCHEMBL6897737

SCHEMBL6897737

COc1[c]c2[nH]c3ccccc3c2cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
KDM4E B2RXH2 5/20 0.45
KMT2A Q03164 4/20 0.45
HSD17B10 Q99714 3/20 0.45
MAPT P10636 3/20 0.45
MEN1 O00255 3/20 0.45
HPGD P15428 2/20 0.45
GPR3 P46089 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
ATM Q13315 2/20 0.41
KIF11 P52732 8/20 0.41
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41
GABRA2 P47869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL328963 0.80 ALDH1A1 (0.41) ALDH1A1KDM4EKMT2AHSD17B10MAPT
SCHEMBL1426545 0.77 KIF11 (0.48) ALDH1A1KDM4EKMT2AHSD17B10MAPT
SCHEMBL5759345 0.74 HSD17B10 (0.37) ALDH1A1KDM4EKMT2AHSD17B10MAPT
SCHEMBL7953010 0.73 ALDH1A1 (0.48) ALDH1A1KDM4EKMT2AHSD17B10MEN1
SCHEMBL8482653 0.73 ALDH1A1 (0.48) ALDH1A1KDM4EKMT2AHSD17B10MAPT
SCHEMBL23212272 0.73 ALDH1A1 (0.48) ALDH1A1KDM4EKMT2AHSD17B10MEN1
SCHEMBL10890967 0.73 ALDH1A1 (0.48) ALDH1A1KDM4EKMT2AHSD17B10MEN1
SCHEMBL11597870 0.73 ALDH1A1 (0.48) ALDH1A1KDM4EKMT2AHSD17B10MAPT
SCHEMBL9010052 0.72 KIF11 (0.49) ALDH1A1KDM4EKMT2AHSD17B10MEN1
SCHEMBL5216846 0.72 KIF11 (0.49) ALDH1A1KDM4EKMT2AHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2004315495-A NEW ARYLAMINE DERIVATIVE HAVING FLUORENE SKELETON, SYNTHETIC INTERMEDIATE OF THE SAME, METHOD FOR PRODUCING THEM AND ORGANIC EL ELEMENT TOSOH CORP 2004-11-11 JP disclosed