Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27649226 | 0.85 | FOLH1 (0.61) | FOLH1SMN1; SMN2 | |
| SCHEMBL10622069 | 0.85 | L3MBTL1 (0.63) | L3MBTL1ATMTDP1PBRM1ALDH1A1 | |
| SCHEMBL4669025 | 0.84 | TDP1 (0.61) | L3MBTL1ATMTDP1PBRM1ALDH1A1 | |
| SCHEMBL7394259 | 0.84 | TDP1 (0.61) | L3MBTL1ATMTDP1PBRM1ALDH1A1 | |
| SCHEMBL11853622 | 0.83 | TDP1 (0.55) | L3MBTL1ATMTDP1PBRM1ALDH1A1 | |
| SCHEMBL3112767 | 0.82 | KEAP1 (0.62) | L3MBTL1ATMTDP1PBRM1ALDH1A1 | |
| SCHEMBL27691637 | 0.82 | L3MBTL1 (0.59) | L3MBTL1ATMTDP1PBRM1ALDH1A1 | |
| SCHEMBL10905589 | 0.82 | ATM (0.59) | L3MBTL1ATMTDP1PBRM1ALDH1A1 | |
| SCHEMBL11301145 | 0.82 | TDP1 (0.59) | L3MBTL1ATMTDP1PBRM1ALDH1A1 | |
| SCHEMBL5207992 | 0.81 | CYP4F2 (0.45) | ALDH1A1CNR2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268526-B1 | MIXTURE FORMED FROM AN AROMATIC SUBSTITUTED ALCOHOL AND/OR AN AROMATIC SUBSTITUTED ALKYL HALIDE, AND A COPPER-FREE PALLADIUM CATALYST IS CARBONYLATED WITH CARBON MONOXIDE TO PRODUCE ALPHA-SUBSTITUTED CARBOXYLIC ACID OR ESTER | ALBEMARLE CORPORATION | 2001-07-31 | — | — | US | disclosed |
| WO-2000035849-A1 | PALLADIUM CATALYZED CARBONYLATION PROCESS | ALBEMARLE CORPORATION (US) | 2000-06-22 | — | — | WO | disclosed |
| US-4329507-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1982-05-11 | — | — | US | disclosed |