SCHEMBL7953281

SCHEMBL7953281

Cc1cccc(C)c1C(Cl)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.41
ATM Q13315 1/20 0.41
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 3/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
L3MBTL1 Q9Y468 4/20 0.38
MYC P01106 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
SLC1A3 P43003 1/20 0.36
SLC1A2 P43004 1/20 0.36
SLC1A1 P43005 1/20 0.36
KMT2A Q03164 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1922886 0.81 HSP90AA1 (0.37) HSP90AA1ATMALDH1A1KDM4EHPGD
SCHEMBL18076238 0.78 ATM (0.39) HSP90AA1ATMALDH1A1KDM4EHPGD
SCHEMBL8932201 0.77 L3MBTL1 (0.44) ALDH1A1KDM4EHPGDHSD17B10L3MBTL1
SCHEMBL3151737 0.77 SRC (0.46) HSP90AA1ATMALDH1A1KDM4EHPGD
SCHEMBL3385373 0.77 ACP3 (0.46) HSP90AA1ATMALDH1A1L3MBTL1MYC
SCHEMBL27964847 0.74 ALDH1A1 (0.41) HSP90AA1ATMALDH1A1KDM4EHPGD
SCHEMBL28170792 0.74 CES2 (0.47) ALDH1A1KDM4EKMT2A
SCHEMBL25660562 0.74 GRM1 (0.46) ALDH1A1KDM4EHPGDHSD17B10L3MBTL1
SCHEMBL27557981 0.74 ALDH1A1 (0.55) ALDH1A1KDM4EHPGDHSD17B10MYC
SCHEMBL3060819 0.72 CXCL8 (0.46) ALDH1A1KDM4EHPGDHSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3781552-A1 METHOD FOR PREPARING ESTERS OF N-ACYLATED AMINO ACIDS WITH ACID-LABILE KETONE PROTECTIVE GROUP FUNCTIONS Bayer Aktiengesellschaft (DE) 2021-02-24 EP disclosed
WO-2019201842-A1 METHOD FOR PREPARING ESTERS OF N-ACYLATED AMINO ACIDS WITH ACID-LABILE KETONE PROTECTIVE GROUP FUNCTIONS BAYER AKTIENGESELLSCHAFT (DE) 2019-10-24 WO disclosed
CN-108473402-A Process for preparing substituted 2-arylethanols 拜耳作物科学股份公司 2018-08-31 CN disclosed
CN-107266306-A Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds 拜耳知识产权有限责任公司 2017-10-20 CN disclosed
CN-103980109-B Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds 拜尔农作物科学股份公司 2017-05-03 CN disclosed
CN-103980109-A Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds BAYER CROPSCIENCE AG 2014-08-13 CN disclosed
CN-102471215-B Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds BAYER CROPSCIENCE AG 2014-06-11 CN disclosed
CN-102471215-A Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds BAYER CROPSCIENCE AG 2012-05-23 CN disclosed
US-6271180-B2 INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-08-07 US disclosed