Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 5/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955637 | 0.94 | SIRT1 (0.54) | ALDH1A1TSHRMAPK1MAPTNPSR1 | |
| SCHEMBL3229725 | 0.82 | ADORA2A (0.47) | ADORA2AADORA2BADORA1P2RX3 | |
| SCHEMBL7091169 | 0.77 | ADORA2B (0.48) | ALDH1A1TSHRMAPK1HPGDSIRT1 | |
| SCHEMBL3111144 | 0.77 | ADORA2B (0.48) | ALDH1A1TSHRMAPK1HPGDSIRT1 | |
| SCHEMBL3231585 | 0.74 | ADORA2A (0.57) | ADORA2AADORA2BADORA1 | |
| SCHEMBL13940893 | 0.74 | ADORA2B (0.60) | ALDH1A1MEN1KMT2AADORA2AADORA2B | |
| SCHEMBL7091342 | 0.71 | KDM4E (0.42) | ALDH1A1TSHRMAPK1MAPTNPSR1 | |
| SCHEMBL7953405 | 0.71 | ADORA2A (0.41) | ALDH1A1TSHRMAPK1MAPTNPSR1 | |
| SCHEMBL7424585 | 0.70 | SIRT1 (0.58) | TSHRMEN1KMT2ASIRT1SIRT3 | |
| SCHEMBL7091149 | 0.69 | P2RX3 (0.41) | ALDH1A1TSHRMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268373-B1 | ENZYME INHIBITORS | EURO-CELTIQUE S.A. (LU) | 2001-07-31 | — | — | US | disclosed |