SCHEMBL7953589

SCHEMBL7953589

[CH2][C](C)c1ccc(C)cc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.52
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
TP53 P04637 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
LMNA P02545 3/20 0.43
CHRM1 P11229 1/20 0.43
SLC6A2 P23975 1/20 0.43
ADRA1A P35348 1/20 0.43
HTR2B P41595 1/20 0.43
CSNK2A1 P68400 1/20 0.42
MAPT P10636 3/20 0.41
HPGD P15428 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HTT P42858 1/20 0.41
KCNH2 Q12809 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ALOX15 P16050 2/20 0.41
HSD17B10 Q99714 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL7951790 0.92 CSNK2A1 (0.50) TRPA1NPC1RAB9ALMNACSNK2A1
SCHEMBL7941793 0.86 CSNK2A1 (0.44) TRPA1NPC1RAB9ALMNACHRM1
SCHEMBL686122 0.82 TRPA1 (0.52) TRPA1NPC1RAB9ATP53TDP1
SCHEMBL22078964 0.77 TRPA1 (0.52) TRPA1NPC1RAB9ATP53TDP1
SCHEMBL760290 0.77 ALDH1A1 (0.57) TRPA1NPC1RAB9ALMNACSNK2A1
SCHEMBL29495480 0.77 ALDH1A1 (0.57) TRPA1NPC1RAB9ALMNACSNK2A1
SCHEMBL7948005 0.77 TRPA1 (0.52) TRPA1NPC1RAB9ATP53TDP1
SCHEMBL14345562 0.76 TRPA1 (0.50) TRPA1NPC1RAB9ATP53TDP1
SCHEMBL11286832 0.76 TRPA1 (0.50) TRPA1NPC1RAB9ATP53TDP1
SCHEMBL11064533 0.76 TRPA1 (0.50) TRPA1NPC1RAB9ATP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111991441-A Anti-inflammatory pharmaceutical composition and application thereof 咸阳职业技术学院 2020-11-27 CN disclosed
US-6255517-B1 6-SULFONYLOXYISOPROPENYL-M-CRESOL AND ESTERS Zee, Ok Pyo (KR) 2001-07-03 US disclosed