Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | DRD4 | P21917 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953790 | 0.80 | DRD2 (0.42) | MAPTDRD4MEN1KMT2AKDM4E | |
| SCHEMBL7953787 | 0.80 | KDM4E (0.37) | USP2TSHRMAPTDRD4MEN1 | |
| SCHEMBL7964959 | 0.78 | HTR1A (0.69) | HTR1A | |
| SCHEMBL22639941 | 0.75 | KMT2A (0.89) | USP2TSHRMAPTDRD4MEN1 | |
| SCHEMBL22639939 | 0.75 | KMT2A (0.89) | USP2TSHRMAPTDRD4MEN1 | |
| SCHEMBL4579320 | 0.74 | USP2 (1.00) | USP2TSHRMAPTMEN1KMT2A | |
| SCHEMBL8145712 | 0.73 | DRD2 (0.48) | MEN1KMT2AHTR1AHTR7DRD2 | |
| SCHEMBL12577241 | 0.73 | DRD4 (0.84) | USP2TSHRMAPTDRD4MEN1 | |
| SCHEMBL22639925 | 0.72 | TSHR (0.88) | USP2TSHRMAPTKMT2AKDM4E | |
| SCHEMBL10200142 | 0.72 | TSHR (0.88) | USP2TSHRMAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |