Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953789 | 0.80 | USP2 (0.56) | KDM4ELMNAMAPTMAPK1MEN1 | |
| SCHEMBL7953790 | 0.78 | DRD2 (0.42) | KDM4ELMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7964956 | 0.78 | HTR1A (0.47) | SLC6A4 | |
| SCHEMBL7963097 | 0.70 | HRH3 (0.36) | KDM4ELMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8145712 | 0.69 | DRD2 (0.48) | MEN1KMT2ADRD2SLC6A4 | |
| SCHEMBL7965447 | 0.69 | HRH3 (0.36) | KDM4ESMN1; SMN2MAPTHPGDMAPK1 | |
| SCHEMBL7962994 | 0.68 | DRD2 (0.38) | CYP2D6DRD3DRD2SLC6A4 | |
| SCHEMBL7966948 | 0.68 | OPRM1 (0.39) | KDM4ELMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL13728399 | 0.67 | CYP11B2 (0.42) | KDM4ELMNACYP3A4KMT2AKDM1A | |
| Acrylic Acid SCHEMBL7963757 | 0.67 | ALDH1A1 (0.38) | LMNASMN1; SMN2MAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| WO-2000006166-A1 | 5-HT1F ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |