Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CTSD | P07339 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945830 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL29678391 | 0.84 | TSHR (0.71) | ALDH1A1KMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL873499 | 0.84 | TSHR (0.71) | ALDH1A1KMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL6895565 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL7945979 | 0.83 | TSHR (0.54) | ALDH1A1KMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL7632342 | 0.83 | CTSD (0.51) | ALDH1A1KMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL514314 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL7945823 | 0.83 | HSD17B10 (0.61) | ALDH1A1KMT2AHPGDESR1TSHR | |
| SCHEMBL11463319 | 0.82 | TSHR (0.61) | ALDH1A1L3MBTL1NPC1TSHRMAPK1 | |
| SCHEMBL7956545 | 0.82 | TSHR (0.55) | ALDH1A1KMT2AHTTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |