Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | CTSD | P07339 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29678391 | 0.85 | TSHR (0.71) | ALDH1A1L3MBTL1HTTKMT2ANPC1 | |
| SCHEMBL873499 | 0.85 | TSHR (0.71) | ALDH1A1L3MBTL1HTTKMT2ANPC1 | |
| SCHEMBL27986491 | 0.84 | TSHR (0.61) | ALDH1A1L3MBTL1NPC1SMN1; SMN2LMNA | |
| SCHEMBL7954423 | 0.84 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1HTTKMT2ANPC1 | |
| SCHEMBL514315 | 0.84 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1HTTKMT2ANPC1 | |
| SCHEMBL2352850 | 0.83 | HTT (0.50) | ALDH1A1HTTKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL10499171 | 0.83 | TSHR (0.57) | ALDH1A1L3MBTL1KMT2AATMLMNA | |
| SCHEMBL12715452 | 0.82 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1HTTKMT2ANPC1 | |
| SCHEMBL16178026 | 0.82 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1HTTKMT2ANPC1 | |
| SCHEMBL2612556 | 0.82 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1HTTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2822938-B1 | RODENTICIDAL NORBORMIDE ANALOGUES | LANDCARE RES NEW ZEALAND LIMITED (NZ) | 2019-07-03 | — | — | EP | disclosed |
| CN-106588644-B | A kind of synthetic method of carboxylic acid ester compound | 杭州师范大学 | 2019-03-29 | — | — | CN | disclosed |
| CN-106588644-A | Synthesis method of carboxylic ester compound | 杭州师范大学 | 2017-04-26 | — | — | CN | disclosed |
| US-9198420-B2 | Rodenticidal norbormide analogues | LANDCARE RESEARCH NEW ZEALAND LIMITED (NZ) | 2015-12-01 | — | — | US | disclosed |
| US-20150025113-A1 | RODENTICIDAL NORBORMIDE ANALOGUES | ANIMAL CONTROL PRODUCTS LIMITED (NZ) | 2015-01-22 | — | — | US | disclosed |
| EP-2822938-A1 | RODENTICIDAL NORBORMIDE ANALOGUES | Landcare Research New Zealand Limited (NZ) | 2015-01-14 | — | — | EP | disclosed |
| WO-2013133726-A1 | RODENTICIDAL NORBORMIDE ANALOGUES | LANDCARE RESEARCH NEW ZEALAND LIMITED (NZ) | 2013-09-12 | — | — | WO | disclosed |
| US-6677331-B2 | HAVING SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP AT 2-POSITION; MICROBIOCIDES AGAINST BETA-LACTAMASE PRODUCING BACTERIA AND RESISTANT PSEUDOMONAS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-13 | — | — | US | disclosed |
| US-20030149016-A1 | Novel carbapenem derivatives | KANO YUKO (JP) | 2003-08-07 | — | — | US | disclosed |
| US-6458780-B1 | IMIDAZO(5,1-B)THIAZOLE GROUP AT THE 2-POSITION ON THE CARBAPENEM RING HAVE HIGH ANTI-MICROBIAL ACTIVITIES AGAINST .BETA.-LACTAMASE PRODUCING BACTERIA, MRSA, RESISTANT-PSEUDOMONAS AERUGINOSA, PRSP, ENTEROCOCCI, AND | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-10-01 | — | — | US | disclosed |
| EP-1101766-A1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150025113-A1 | RODENTICIDAL NORBORMIDE ANALOGUES | CASP7, RANBP1, CASP3 | ALDH1A1 1772/4885L3MBTL1 1112/4885HTT 3920/4885 |
| US-20030149016-A1 | Novel carbapenem derivatives | DPEP1, TMPRSS15, STK35 | ALDH1A1 1161/4885L3MBTL1 2671/4885HTT 3821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.