Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.40 |
| ▸ | ADH1C | P00326 | 1/20 | 0.40 |
| ▸ | ADH1A | P07327 | 1/20 | 0.40 |
| ▸ | ADH7 | P40394 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8252 | 0.81 | CYP3A4 (0.52) | SIGMAR1MAPTCYP3A4KDM4EIDO1 | |
| Bromide SCHEMBL28406943 | 0.79 | CYP3A4 (0.50) | SIGMAR1MAPTCYP3A4KDM4EIDO1 | |
| SCHEMBL6492992 | 0.78 | ALDH1A1 (0.53) | MAPTIDO1MEN1KMT2AL3MBTL1 | |
| SCHEMBL28518697 | 0.78 | MEN1 (0.49) | MAPTIDO1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8131169 | 0.76 | SIGMAR1 (0.48) | SIGMAR1MAPTCYP3A4KDM4EIDO1 | |
| Naphthalene SCHEMBL9463547 | 0.76 | CYP3A4 (0.46) | SIGMAR1MAPTCYP3A4KDM4EIDO1 | |
| SCHEMBL11661655 | 0.75 | IDO1 (0.52) | MAPTCYP3A4KDM4EIDO1THRB | |
| SCHEMBL5179520 | 0.74 | CYP3A4 (0.45) | SIGMAR1MAPTCYP3A4KDM4EIDO1 | |
| SCHEMBL28377529 | 0.74 | CYP3A4 (0.45) | SIGMAR1MAPTCYP3A4KDM4EIDO1 | |
| Methoxymethane SCHEMBL10589288 | 0.73 | MEN1 (0.64) | MAPTCYP3A4KDM4ETHRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329373-B1 | AMIDES WITH HYDROXYAMIDES AS ENZYME INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS, LTD. (GB) | 2001-12-11 | — | — | US | disclosed |