Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6492992 | 0.79 | ALDH1A1 (0.53) | MEN1KMT2ANPC1GAAMAPT | |
| SCHEMBL7955870 | 0.78 | SIGMAR1 (0.50) | MEN1KMT2AMAPTL3MBTL1IDO1 | |
| SCHEMBL12605293 | 0.78 | CYP1A2 (0.44) | MEN1KMT2ANPC1GAAMAPT | |
| SCHEMBL16302331 | 0.75 | CYP1A2 (0.42) | MEN1KMT2ANPC1GAAMAPT | |
| SCHEMBL596900 | 0.70 | TAAR1 (0.60) | MEN1KMT2ANPC1GAAMAPT | |
| SCHEMBL2548456 | 0.70 | PYCR1 (0.48) | MEN1KMT2ANPC1GAAMAPT | |
| SCHEMBL8151807 | 0.69 | PYCR1 (0.64) | MEN1KMT2ANPC1GAAMAPT | |
| Hydrochloric Acid SCHEMBL8153066 | 0.69 | MAPT (0.58) | MEN1KMT2ANPC1GAAMAPT | |
| SCHEMBL1241301 | 0.68 | L3MBTL1 (0.62) | MEN1KMT2ANPC1GAAMAPT | |
| SCHEMBL2755804 | 0.68 | TSHR (0.59) | MEN1KMT2AGAAL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112292129-A | Novel compounds and pharmaceutical compositions thereof for the treatment of diseases | 加拉帕戈斯股份有限公司 | 2021-01-29 | — | — | CN | disclosed |