Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968732 | 0.89 | L3MBTL1 (0.38) | EBPSIGMAR1CYP3A4CYP2D6AR | |
| SCHEMBL7956534 | 0.87 | EBP (0.38) | EBPSIGMAR1CYP3A4CYP2D6AR | |
| SCHEMBL7968543 | 0.86 | EBP (0.36) | EBPSIGMAR1CYP3A4CYP2D6AR | |
| SCHEMBL7966692 | 0.86 | EBP (0.36) | EBPSIGMAR1CYP3A4CYP2D6AR | |
| SCHEMBL7972427 | 0.84 | SIGMAR1 (0.39) | EBPSIGMAR1L3MBTL1 | |
| SCHEMBL7965668 | 0.84 | EBP (0.43) | EBPSIGMAR1CYP3A4CYP2D6AR | |
| SCHEMBL7965708 | 0.84 | EBP (0.39) | EBPSIGMAR1CYP3A4CYP2D6S1PR1 | |
| SCHEMBL7955946 | 0.83 | SIGMAR1 (0.47) | EBPSIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL7971287 | 0.82 | AR (0.39) | EBPSIGMAR1CYP3A4CYP2D6AR | |
| SCHEMBL7971788 | 0.81 | EBP (0.36) | EBPSIGMAR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265439-B1 | Halogenated phenylacetonitrile alkylaminoalkylphenyl compounds as immunosuppressives | G.D. SEARLE & CO. | 2001-07-24 | — | — | US | disclosed |