Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EBP | Q15125 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968732 | 0.89 | L3MBTL1 (0.38) | ARPGRL3MBTL1EBPSIGMAR1 | |
| SCHEMBL7971971 | 0.89 | L3MBTL1 (0.38) | ARPGRL3MBTL1EBPSIGMAR1 | |
| SCHEMBL7972161 | 0.87 | AR (0.41) | ARPGRL3MBTL1EBPSIGMAR1 | |
| SCHEMBL7965756 | 0.86 | EBP (0.43) | ARPGREBPSIGMAR1SLC6A4 | |
| SCHEMBL7969390 | 0.86 | L3MBTL1 (0.38) | ARPGRL3MBTL1EBPSIGMAR1 | |
| SCHEMBL7971426 | 0.84 | EBP (0.39) | ARPGRL3MBTL1EBPSIGMAR1 | |
| SCHEMBL7971289 | 0.83 | SIGMAR1 (0.47) | L3MBTL1EBPSIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL7968543 | 0.82 | EBP (0.36) | ARPGRL3MBTL1EBPSIGMAR1 | |
| SCHEMBL7955944 | 0.82 | EBP (0.36) | ARL3MBTL1EBPSIGMAR1CYP3A4 | |
| SCHEMBL7968647 | 0.82 | EBP (0.43) | ARPGRL3MBTL1EBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265439-B1 | Halogenated phenylacetonitrile alkylaminoalkylphenyl compounds as immunosuppressives | G.D. SEARLE & CO. | 2001-07-24 | — | — | US | disclosed |