Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 4/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969791 | 0.88 | L3MBTL1 (0.40) | EBPSIGMAR1RIPK1L3MBTL1CYP2D6 | |
| SCHEMBL7955944 | 0.87 | EBP (0.36) | EBPSIGMAR1RIPK1L3MBTL1CYP2D6 | |
| SCHEMBL7968796 | 0.85 | EBP (0.38) | EBPSIGMAR1RIPK1L3MBTL1CYP2D6 | |
| SCHEMBL7972392 | 0.85 | EBP (0.38) | EBPSIGMAR1RIPK1L3MBTL1CYP2D6 | |
| SCHEMBL7965566 | 0.83 | ADRA2B (0.43) | EBPSIGMAR1CYP2D6CYP3A4HTR2A | |
| SCHEMBL7968582 | 0.83 | EBP (0.46) | EBPSIGMAR1RIPK1L3MBTL1CYP2D6 | |
| SCHEMBL7968615 | 0.83 | EBP (0.46) | EBPSIGMAR1RIPK1L3MBTL1CYP2D6 | |
| SCHEMBL7965265 | 0.82 | EBP (0.41) | EBPSIGMAR1CYP2D6CYP3A4DRD2 | |
| SCHEMBL7956537 | 0.81 | SIGMAR1 (0.50) | EBPSIGMAR1CYP2D6CYP3A4DRD2 | |
| SCHEMBL7972161 | 0.81 | AR (0.41) | EBPSIGMAR1RIPK1L3MBTL1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265439-B1 | Halogenated phenylacetonitrile alkylaminoalkylphenyl compounds as immunosuppressives | G.D. SEARLE & CO. | 2001-07-24 | — | — | US | disclosed |