Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178255 | 0.85 | HTR1A (0.45) | HTR1AKMT2AMEN1OPRD1OPRK1 | |
| SCHEMBL7958707 | 0.84 | HTR1A (0.43) | HTR1AKMT2AMEN1OPRD1OPRK1 | |
| SCHEMBL7759804 | 0.80 | MEN1 (0.46) | KMT2AMEN1MAPK1CHRM4CACNA1G | |
| SCHEMBL6176757 | 0.77 | KMT2A (0.48) | KMT2AMEN1MAPK1CHRM4DRD2 | |
| SCHEMBL27509799 | 0.76 | KMT2A (0.47) | KMT2AMEN1MAPK1CHRM4CHRM1 | |
| SCHEMBL6177901 | 0.76 | MEN1 (0.50) | HTR1AKMT2AMEN1MAPK1CHRM4 | |
| SCHEMBL6176762 | 0.76 | MEN1 (0.51) | KMT2AMEN1MAPK1CHRM4DRD2 | |
| Cyclohexane SCHEMBL6180435 | 0.75 | MEN1 (0.48) | HTR1AKMT2AMEN1MAPK1CHRM4 | |
| SCHEMBL6177497 | 0.74 | MEN1 (0.51) | KMT2AMEN1MAPK1DRD2 | |
| Cyclohexane SCHEMBL6178387 | 0.73 | MEN1 (0.48) | HTR1AKMT2AMEN1MAPK1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326381-B1 | PSYCHOLOGICAL DISORDERS; NERVOUS SYSTEM DISORDERS | AMERICAN HOME PRODUCTS CORPORATION | 2001-12-04 | — | — | US | claimed |