Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993559 | 1.00 | LMNA (0.43) | LMNAALDH1A1GABRA1GABRB2PTGS1 | |
| SCHEMBL7570629 | 0.84 | GABRA1 (0.40) | LMNAALDH1A1GABRA1GABRB2ESR1 | |
| SCHEMBL7564062 | 0.75 | KDM4E (0.55) | LMNAALDH1A1CDK1CCNB1GSK3A | |
| SCHEMBL3363408 | 0.75 | KDM4E (0.55) | LMNAALDH1A1CDK1CCNB1GSK3A | |
| SCHEMBL7565537 | 0.75 | KDM4E (0.55) | LMNAALDH1A1CDK1CCNB1GSK3A | |
| SCHEMBL7567255 | 0.74 | ALDH1A1 (0.50) | LMNAALDH1A1CYP2C9TSHRCDK1 | |
| SCHEMBL6931344 | 0.72 | ALDH1A1 (0.45) | LMNAALDH1A1CYP2C9EPHX1CDK1 | |
| SCHEMBL6929228 | 0.70 | ALDH1A1 (0.47) | LMNAALDH1A1CYP2C9ALOX5TSHR | |
| SCHEMBL7030920 | 0.70 | ALDH1A1 (0.43) | LMNAALDH1A1GABRA1GABRB2EPHX1 | |
| SCHEMBL6026843 | 0.70 | ME2 (0.46) | LMNAALDH1A1PTGS2TSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746551-A1 | OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1996-12-11 | — | — | EP | disclosed |