Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766489 | 0.87 | HDAC1 (0.60) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| Ammonia Solution, Strong SCHEMBL27769629 | 0.85 | HDAC1 (0.57) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL796354 | 0.83 | HDAC7 (0.34) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| Valproic Acid SCHEMBL795762 | 0.81 | CHRM1 (0.76) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL7061425 | 0.80 | — | — | |
| SCHEMBL12559160 | 0.78 | CA2 (0.54) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL17244095 | 0.78 | HDAC1 (0.50) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL13636208 | 0.77 | — | — | |
| SCHEMBL5377086 | 0.77 | — | — | |
| SCHEMBL14203373 | 0.76 | HDAC7 (0.48) | HDAC7HDAC8HDAC6HDAC9HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071554-A1 | DEUTERATED 2-PROPYLPENTANOIC ACID COMPOUNDS | CONCERT PHARMACEUTICALS INC. | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071554-A1 | DEUTERATED 2-PROPYLPENTANOIC ACID COMPOUNDS | GABRD, GABRA5, GABRA2 | HDAC7 21/4885HDAC8 18/4885HDAC6 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.