Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDO2 | P48775 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435518 | 0.85 | CYP1A1 (0.54) | CYP11B2CYP11B1ALDH1A1TDO2MAPT | |
| SCHEMBL8436212 | 0.85 | CYP11B2 (0.39) | CYP11B2CYP11B1TDO2MAPTCYP19A1 | |
| SCHEMBL7971923 | 0.83 | CHRM5 (0.47) | MAPTCYP1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8911420 | 0.82 | ALDH1A1 (0.62) | CYP11B2CYP11B1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7968716 | 0.81 | POLB (0.41) | CYP11B2CYP11B1ALDH1A1MAPTGAA | |
| SCHEMBL27515192 | 0.81 | MAPT (0.54) | CYP11B2CYP11B1ALDH1A1TDO2MAPT | |
| SCHEMBL7969830 | 0.77 | TP53 (0.43) | MAPTGAALMNATDP1CYP1A2 | |
| SCHEMBL7958255 | 0.76 | NPC1 (0.40) | ALDH1A1MAPTNFE2L2L3MBTL1RAB9A | |
| SCHEMBL3142532 | 0.76 | CYP11B2 (0.68) | CYP11B2CYP11B1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7974639 | 0.74 | CHRM5 (0.46) | ALDH1A1GAACYP19A1CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |