Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971923 | 0.86 | CHRM5 (0.47) | MAOAMAOBMAPTCYP1A2CYP3A4 | |
| SCHEMBL18240555 | 0.82 | TP53 (0.52) | TP53TDP1NPC1CASP3SENP8 | |
| SCHEMBL8436212 | 0.80 | CYP11B2 (0.39) | MAOBMAPTCHRM5 | |
| SCHEMBL7974639 | 0.80 | CHRM5 (0.46) | NPC1CYP1A2CYP3A4KDM4ERELA | |
| SCHEMBL3302772 | 0.78 | TP53 (0.65) | TP53TDP1NPC1CASP3SENP8 | |
| SCHEMBL7958570 | 0.77 | CYP11B2 (0.46) | TDP1NPC1MAPTCYP1A2LMNA | |
| SCHEMBL7972130 | 0.75 | ALOX5 (0.44) | MAPTLMNAPTGS1PTGS2ALOX5 | |
| SCHEMBL7972129 | 0.74 | ALDH1A1 (0.50) | TDP1NPC1MAOBMAPTLMNA | |
| SCHEMBL8438601 | 0.73 | CHRM5 (0.42) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7968716 | 0.73 | POLB (0.41) | TDP1NPC1MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |