Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.53 |
| ▸ | RARA | P10276 | 1/20 | 0.53 |
| ▸ | CCR5 | P51681 | 9/20 | 0.38 |
| ▸ | CCR7 | P32248 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7247416 | 0.95 | RARB (0.46) | RARBRARACCR5TSHR | |
| SCHEMBL7972262 | 0.95 | RARB (0.45) | RARBRARATP53TSHR | |
| SCHEMBL7958827 | 0.92 | RARB (0.42) | RARBRARA | |
| SCHEMBL7252964 | 0.91 | RARB (0.40) | RARBRARATSHR | |
| SCHEMBL7931697 | 0.87 | RXRA (0.41) | CCR5 | |
| SCHEMBL7975157 | 0.85 | RARB (0.40) | RARBRARACCR5CCR7CCR2 | |
| SCHEMBL7222487 | 0.85 | RARB (0.38) | RARBRARATP53TSHR | |
| SCHEMBL7928473 | 0.85 | ALPL (0.43) | RARBRARA | |
| SCHEMBL7249525 | 0.85 | RARB (0.39) | RARBRARACCR5 | |
| SCHEMBL7215961 | 0.83 | HRH3 (0.39) | RARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |