Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 10/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9382711 | 0.87 | LMNA (0.39) | ERN1LMNAMAPK1RAB9ASLC6A15 | |
| SCHEMBL7956038 | 0.85 | LMNA (0.37) | ERN1LMNAMAPK1RAB9ASLC6A15 | |
| SCHEMBL11554285 | 0.82 | MAPT (0.42) | LMNAMEN1KMT2A | |
| SCHEMBL30564477 | 0.81 | LMNA (0.40) | ERN1LMNAMAPK1RAB9ASLC6A15 | |
| SCHEMBL7962633 | 0.81 | LMNA (0.35) | ERN1LMNAMAPK1RAB9ASLC6A15 | |
| SCHEMBL11578372 | 0.78 | SMN1; SMN2 (0.37) | LMNARAB9ASLC6A15GRM5 | |
| SCHEMBL11560889 | 0.76 | GRM5 (0.57) | RAB9AGRM5MEN1KMT2A | |
| SCHEMBL11556626 | 0.76 | SMN1; SMN2 (0.48) | LMNARAB9ACHRM1MEN1KMT2A | |
| SCHEMBL9384934 | 0.75 | LMNA (0.38) | ERN1LMNAMAPK1RAB9ACYP3A4 | |
| SCHEMBL11580323 | 0.75 | CYP2C19 (0.38) | MAPK1RAB9ACYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265396-B1 | ACTIVITY AGAINST GRAM-POSITIVE BACTERIA, PARTICULARLY AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCI AND METHICILLIN-RESISTANT AND COAGULASE-NEGATIVE STAPHYLOCOCCI. | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-0934942-A1 | NOVEL BETA-LACTAM COMPOUNDS AND PROCESS FOR PREPARING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-08-11 | — | — | EP | disclosed |