Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 9/20 | 0.35 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958636 | 0.81 | ERN1 (0.43) | LMNAMAPK1RAB9AERN1SLC6A15 | |
| SCHEMBL9382711 | 0.80 | LMNA (0.39) | LMNAMAPK1RAB9AERN1SLC6A15 | |
| SCHEMBL7956038 | 0.75 | LMNA (0.37) | LMNAMAPK1RAB9AERN1SLC6A15 | |
| SCHEMBL30564477 | 0.72 | LMNA (0.40) | LMNAMAPK1RAB9AERN1SLC6A15 | |
| SCHEMBL9384934 | 0.69 | LMNA (0.38) | LMNAMAPK1RAB9AERN1 | |
| SCHEMBL11554285 | 0.67 | MAPT (0.42) | LMNA | |
| SCHEMBL20314882 | 0.66 | PDK4 (0.52) | PDK4 | |
| SCHEMBL6214637 | 0.65 | MAPT (0.43) | LMNA | |
| SCHEMBL26091050 | 0.65 | ERN1 (0.44) | LMNAMAPK1RAB9AERN1SLC6A15 | |
| SCHEMBL597800 | 0.65 | LMNA (0.45) | LMNAMAPK1RAB9AERN1SLC6A15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265396-B1 | ACTIVITY AGAINST GRAM-POSITIVE BACTERIA, PARTICULARLY AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCI AND METHICILLIN-RESISTANT AND COAGULASE-NEGATIVE STAPHYLOCOCCI. | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-0934942-A1 | NOVEL BETA-LACTAM COMPOUNDS AND PROCESS FOR PREPARING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-08-11 | — | — | EP | disclosed |