Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 3/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958949 | 0.87 | NPC1 (0.38) | NPC1RAB9ALMNACASP3SENP8 | |
| SCHEMBL10503546 | 0.81 | NPC1 (0.54) | NPC1RAB9ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL10247598 | 0.81 | RAB9A (0.46) | NPC1RAB9ALMNACASP3L3MBTL1 | |
| SCHEMBL29915489 | 0.78 | SMPD1 (0.48) | NPC1RAB9AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL10247672 | 0.77 | L3MBTL1 (0.51) | NPC1RAB9ACASP3L3MBTL1ALDH1A1 | |
| SCHEMBL10250868 | 0.77 | NPC1 (0.49) | NPC1RAB9ALMNACASP3SENP8 | |
| SCHEMBL10247668 | 0.77 | NPC1 (0.56) | NPC1RAB9ALMNACASP3SENP8 | |
| SCHEMBL10247596 | 0.74 | ALDH1A1 (0.47) | NPC1RAB9AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL577888 | 0.72 | TSHR (0.40) | LMNAALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL7959543 | 0.70 | NPC1 (0.53) | NPC1RAB9ALMNACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291492-B1 | 3-aryl alkenyl-1,2,4-oxadiazole derivatives and their use as parasiticides for animals | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-18 | — | — | US | disclosed |
| EP-0740664-A1 | 3-ARYL ALKENYL-1,2,4-OXADIAZOLE DERIVATIVES AND THEIR USE AS PARASITICIDES FOR ANIMALS | BAYER AG (DE) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995019354-A1 | 3-ARYL ALKENYL-1,2,4-OXADIAZOLE DERIVATIVES AND THEIR USE AS PARASITICIDES FOR ANIMALS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-20 | — | — | WO | disclosed |