Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29915489 | 0.85 | SMPD1 (0.48) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10247668 | 0.84 | NPC1 (0.56) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL10247672 | 0.82 | L3MBTL1 (0.51) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10247596 | 0.82 | ALDH1A1 (0.47) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7958952 | 0.81 | NPC1 (0.40) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10247598 | 0.80 | RAB9A (0.46) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10250868 | 0.79 | NPC1 (0.49) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10475793 | 0.78 | NOTUM (0.63) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL91656 | 0.75 | SMN1; SMN2 (0.70) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9863391 | 0.75 | NOTUM (0.51) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123378-B1 | 1-NORMONYL DERIVATIVES, PROCESSES AND USE | BEECHAM GROUP PLC (GB) | 1989-09-06 | — | — | EP | disclosed |
| US-4861788-A | FUNGICIDE, BACTERICIDE | BEECHAM GROUP PLC (GB) | 1989-08-29 | — | — | US | disclosed |
| EP-0123378-A2 | 1-Normonyl derivatives, processes and use | BEECHAM GROUP PLC (GB) | 1984-10-31 | — | — | EP | disclosed |