SCHEMBL7959308

SCHEMBL7959308

COC(=O)C(CBr)(c1ccccc1)C1CCCCO1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 3/20 0.43
KCNN4 O15554 1/20 0.40
CHRM2 P08172 6/20 0.39
CHRM4 P08173 6/20 0.39
CHRM1 P11229 6/20 0.39
CHRM3 P20309 6/20 0.39
ALDH1A1 P00352 1/20 0.38
ITGB1 P05556 1/20 0.37
ITGA4 P13612 1/20 0.37
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
POLB P06746 1/20 0.37
CYP2C19 P33261 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
PKM P14618 1/20 0.36
NFKB1 P19838 1/20 0.36
THPO P40225 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5686699 0.71 SLC6A3 (0.45) SLC6A3KCNN4CHRM2CHRM4CHRM1
SCHEMBL8762985 0.70 KEAP1 (0.46) SLC6A3ALDH1A1KEAP1NFE2L2CYP1A2
SCHEMBL4010466 0.68 SLC6A3 (0.43) SLC6A3KCNN4CHRM2CHRM4CHRM1
SCHEMBL38654851 0.68 SLC6A3 (0.36) SLC6A3ALDH1A1
SCHEMBL15106304 0.68 CYP1A2 (0.43) SLC6A3ALDH1A1CYP1A2SIGMAR1
SCHEMBL14300775 0.67 KEAP1 (0.37) SLC6A3ALDH1A1KEAP1NFE2L2CYP2C19
SCHEMBL28542144 0.67 KCNN4 (0.60) KCNN4CHRM2CHRM4CHRM1CHRM3
SCHEMBL8028322 0.67 MEN1 (0.41) SLC6A3ALDH1A1CYP1A2
SCHEMBL7959301 0.66 KCNN4 (0.58) KCNN4CHRM2CHRM4CHRM1CHRM3
SCHEMBL6902537 0.66 KEAP1 (0.36) SLC6A3ALDH1A1KEAP1NFE2L2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313150-B1 FOR CONTROLLING PHYTOPATHOGENIC FUNGI SHIONOGI & CO., LTD. (JP) 2001-11-06 US disclosed
EP-0754672-B1 GAMMA-SUBSTITUTED PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND AGRICULTURAL BACTERICIDE CONTAINING THE SAME SHIONOGI & CO (JP) 2000-10-11 EP disclosed
US-5948819-A α-substituted phenylacetic acid derivative, its production and agricultural fungicide containing it SHIONOGI & CO., LTD (JP) 1999-09-07 US disclosed
EP-0754672-A1 GAMMA-SUBSTITUTED PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND AGRICULTURAL BACTERICIDE CONTAINING THE SAME SHIONOGI & CO., LTD. (JP) 1997-01-22 EP disclosed