SCHEMBL7959836

SCHEMBL7959836

COCCOCOc1ccc(C(Oc2cccc3c2C(=O)NC3=O)C(=O)O)c(Cl)c1OCOCCOC

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.34
FABP4 P15090 1/20 0.33
FABP5 Q01469 1/20 0.33
RARG P13631 7/20 0.33
KCNA5 P22460 1/20 0.32
IKBKB O14920 2/20 0.32
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
RARA P10276 1/20 0.31
RARB P10826 1/20 0.31
STK10 O94804 1/20 0.31
CLK2 P49760 1/20 0.31
GSK3A P49840 1/20 0.31
GSK3B P49841 1/20 0.31
STK33 Q9BYT3 1/20 0.31
SLK Q9H2G2 1/20 0.31
CLK4 Q9HAZ1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7967343 0.90 FABP4 (0.38) CASP3FABP4FABP5RARGKCNA5
SCHEMBL7963652 0.86 CASP3 (0.33) CASP3FABP4FABP5RARGKCNA5
SCHEMBL7964208 0.84 RARG (0.36) CASP3FABP4FABP5RARGIKBKB
SCHEMBL8132547 0.81 CYP1A2 (0.34) CASP3RARGKCNA5IKBKBKDM4E
SCHEMBL7959787 0.80 PTGS1 (0.36) CASP3RARGIKBKBKDM4EALDH1A1
SCHEMBL8119171 0.76 CASP3 (0.36) CASP3RARGKCNA5IKBKBKDM4E
SCHEMBL7962776 0.74 FABP4 (0.38) FABP4FABP5RARGIKBKBRARA
SCHEMBL8128162 0.71 CASP3 (0.34) CASP3RARGKDM4EALDH1A1GAA
SCHEMBL8134794 0.71 RARG (0.35) CASP3RARGIKBKBKDM4EALDH1A1
SCHEMBL7951484 0.67 FABP4 (0.50) FABP4FABP5RARGIKBKBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313305-B1 ANTIBIOTICS, BACTERICIDES HOECHST MARION ROUSSEL (FR) 2001-11-06 US disclosed
US-5587372-A BACERICIDES ROUSSEL UCLAF (FR) 1996-12-24 US disclosed
US-5455238-A Bactericides ROUSSEL UCLAF (FR) 1995-10-03 US disclosed