SCHEMBL7963652

SCHEMBL7963652

COCCOCOc1c(F)ccc(C(Oc2cccc3c2C(=O)NC3=O)C(=O)O)c1OCOCCOC

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 2/20 0.33
FFAR4 Q5NUL3 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
RARG P13631 1/20 0.32
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
EGFR P00533 2/20 0.31
FABP4 P15090 1/20 0.31
FABP5 Q01469 1/20 0.31
KCNA5 P22460 1/20 0.31
PTGER3 P43115 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7967343 0.90 FABP4 (0.38) CASP3KDM4EALDH1A1GAAHPGD
SCHEMBL7959836 0.86 CASP3 (0.34) CASP3KDM4EALDH1A1GAAHPGD
SCHEMBL7959787 0.85 PTGS1 (0.36) CASP3FFAR4KDM4EALDH1A1GAA
SCHEMBL7964208 0.81 RARG (0.36) CASP3KDM4EALDH1A1GAAHPGD
SCHEMBL8128162 0.80 CASP3 (0.34) CASP3FFAR4KDM4EALDH1A1GAA
SCHEMBL8119171 0.74 CASP3 (0.36) CASP3KDM4EALDH1A1GAAHPGD
SCHEMBL7962058 0.73 RARG (0.34) FFAR4KDM4EALDH1A1RARGFABP4
SCHEMBL8167098 0.72 GAA (0.34) CASP3FFAR4KDM4EALDH1A1GAA
SCHEMBL8132547 0.70 CYP1A2 (0.34) CASP3KDM4EALDH1A1GAAHPGD
SCHEMBL8133892 0.67 RAB9A (0.33) GAAHPGDRARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313305-B1 ANTIBIOTICS, BACTERICIDES HOECHST MARION ROUSSEL (FR) 2001-11-06 US disclosed
US-5455238-A Bactericides ROUSSEL UCLAF (FR) 1995-10-03 US disclosed